Momo Kombucha is a UK-based kombucha brand focused on crafting gut-friendly, probiotic-rich drinks using organic teas and a slow fermentation process. Brewed in glass and never pasteurized, their kombucha preserves live cultures and authentic flavor, supporting digestive health and wellness.
Kurk is a wellness beverage brand offering sparkling tonics infused with prebiotics, adaptogens, and botanicals. Their drinks are crafted to enhance digestion, reduce stress, and promote balance—without added sugar or artificial ingredients.
Willy's ACV is a UK-based wellness brand offering organic apple cider vinegar and related gut health products made using wild fermentation and apples from a 300-year-old orchard. The brand focuses on natural remedies to support digestion, immunity, and overall wellness.
ARMRA makes a nutrient-rich colostrum concentrate that protects, restores, and enhances immune health and cellular performance. Sourced from grass-fed cow’s colostrum, their products contain over 400 bioactive nutrients that support immune function, gut health, skin vitality, and more. Using their proprietary Cold-Chain BioPotent Technology, ARMRA ensures the nutrients are preserved in their most potent and bioavailable form.
rmdy was created to give anyone with a gut a preventative & proactive solution for short + long term digestive health that is efficacious, convenient, and delicious.
Seed believes beneficial microbes can play a systems-wide role in human health. Their Daily Synbiotic is a gut health supplement that reflects a commitment to reclaim the term ‘probiotics’ for science and to establish a new standard.
Dr. Berg is a trusted name in health and wellness, known for making complex nutrition science simple and accessible. Specializing in ketogenic and intermittent fasting strategies, Dr. Eric Berg has helped millions take control of their health through educational content, high-quality supplements, and practical guidance. His brand is built on the philosophy that real, sustainable health starts with understanding your body’s needs—focusing on natural ingredients, holistic healing, and evidence-based nutrition. Whether you’re looking to improve energy, support weight loss, or optimize overall wellness, Dr. Berg provides the tools and knowledge to help you thrive.
Fill your medicine cabinet with clean & natural remedies (that actually work). Immune support to energy support.
ZBiotics® is an enhanced probiotic drink that breaks down an unwanted alcohol byproduct called acetaldehyde – the primary culprit behind rough mornings after drinking. Drink a ZBiotic just before going out or right before your first drink to enjoy the rest of your night and wake up feeling as good as new.
Mac 'n' cheese just got a makeover. Co-founded by actress Gal Gadot, Goodles is a healthier macaroni and cheese alternative that has 15g of protein, 6g of fiber, prebiotics to support gut health, and 21 nutrients from organic plants.
Health-Ade is brewed in Los Angeles and contains organic fermented kombucha packed with probiotics and healthy organic acids which are known to support a healthy gut. Health-Ade has also launched 3 new product SKUS Health-Ade Plus, Health-Ade Pop (a soda alternative with prebiotics), and Health-Ade Mixers (probiotic alcohol mixers).
Direct-to-consumer (D2C/DTC) gut health brands are companies that specialize in products designed to improve gastrointestinal health, such as probiotics, prebiotics, and dietary supplements, and sell these products directly to consumers through online platforms. By bypassing traditional retail channels, these brands can offer personalized customer experiences, educational content about gut health, and innovative products tailored to individual health needs.
Brands like Seed, VSL#3, and Culturelle have become leaders in the D2C gut health space, recognized for their scientific approach to product development, transparency in ingredient sourcing, and commitment to customer education on gut health.
The best D2C gut health brands are distinguished by their commitment to scientific research, quality ingredients, and effective formulations. Seed stands out for its use of scientifically-backed probiotic strains in its Synbiotic formula, offering a well-researched approach to improving gut health. VSL#3 is notable for its high-potency probiotic medical food, used under medical supervision for managing conditions like IBS and ulcerative colitis.
Culturelle is widely recognized for its range of probiotics that cater to various health needs, from digestive support to immune health, leveraging clinically studied strains. These brands excel not only in providing high-quality gut health supplements but also in fostering informed communities around gut health and wellness.
The D2C gut health category is currently witnessing several key trends that reflect a growing consumer interest in holistic health and wellness. Personalization is a major trend, with brands offering tailored probiotic and prebiotic formulations based on individual health assessments and gut microbiome testing.
Sustainability and clean labeling are also becoming increasingly important, as consumers seek products with transparent, environmentally friendly practices and ingredients. Furthermore, the integration of technology for enhanced customer engagement and education, such as mobile apps and interactive websites, is on the rise, allowing for a more interactive and informed approach to managing gut health. These trends underscore the shift towards more personalized, sustainable, and tech-driven solutions in the realm of gut health.
Everything you need to build a better D2C brand, business and tech stack.
